A study conducted by the Microbiome working group at the Enteric Diseases Division, Manipal Academy of Higher Education (MAHE), has placed India on the global map in Parkinson’s disease research. This landmark research explores the connection between the gut microbiome and Parkinson’s disease, a critical step in understanding this neurodegenerative disorder that primarily affects the elderly.
The team, led by Dr. Mamatha Ballal and comprising Dr. Sujith Pavan, Dr. Sankar Prasad Gorthi, Dr. Arvind Prabhu, Dr. Bhabatosh Das, Dr. Ankur Mutreja, Dr. Vignesh Shetty, Dr. Ramamurthy, and Dr. Karthick Vasudevan, has made a significant contribution by investigating the intestinal microbial profile of Indian individuals with Parkinson’s disease. Their study reveals that Parkinson’s disease patients have a distinct gut bacterial profile compared to healthy individuals, offering new insights into the disease’s development and progression.
Parkinson’s disease, the second most common neurodegenerative disorder globally, is characterized by tremors, muscle stiffness, and balance issues. Currently, there is no cure, and treatments focus on improving life quality. Recent studies highlight gut dysbiosis’ role in Parkinson’s disease development and progression. The MAHE team’s research on gut microbiome and Parkinson’s disease is a significant milestone in Indian science and international Parkinson’s research, highlighting the potential for improved diagnosis and treatment strategies.
